At ELRIG Drug Discovery 2025, Blake Forman spoke to Jordan Lane and Layla Hosseini-Gerami about how we use AI to uncover the hidden mechanisms of drug toxicity.
"By harnessing the power of artificial intelligence (AI) and focusing on drugs that have already shown promise, they hope to accelerate development timelines, reduce clinical risk and cut carbon emissions.
Jordan Lane, PhD: Leaving good science on the shelf is heartbreaking. I’ve seen projects and companies fail during the clinical trial stages. Discovering that a promising drug is producing off-target effects during clinical trials means that it probably could have been saved at some point. There are many examples of this in the industry. Our ability to use AI to “rescue” these molecules is really powerful.
Layla Hosseini-Gerami, PhD: We see this as a bit of a contrast to other uses of AI in the industry, where many applications are focused on trying to get more drugs into the funnel, whereas we're really focusing on rescuing drugs when they drop out of the funnel."
Read more:
Old drug, new tricks: AI helps rescue failed medicines can be read in full at Technology Networks.
Published: 2 December 2025 by Technology Networks.
